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The ingredient list on the Gusupy Super Mushroom Gummies label runs 12 species deep. For buyers who want to understand what they are actually taking — what each mushroom is, what it is studied for, and why multi-mushroom blends are formulated the way they are — this breakdown covers each ingredient individually.
All research references below pertain to studies on individual mushroom species or isolated compounds. None of this information constitutes a claim about the Gusupy finished product, which is a dietary supplement not evaluated by the FDA for disease treatment or prevention.
Fruiting Body 10:1 Extracts: Why Sourcing and Concentration Both Matter
Before getting into species, the two label details worth understanding for every mushroom in this formula:
Fruiting body: The mushroom cap and stem — the reproductive structure of the fungus. This is the part that concentrates the highest levels of beta-glucan polysaccharides and species-specific bioactives. The alternative is mycelium grown on grain substrate, which can contain substantial amounts of residual starch that dilutes the active compound content. Gusupy specifies fruiting body for all 12 ingredients. This is the preferred designation in the functional mushroom supplement community.
10:1 extract ratio: Ten parts of raw fruiting body were used to produce one part of concentrated extract. At 300mg of Lion’s Mane per serving with a 10:1 ratio, the serving delivers the equivalent concentrated from 3,000mg of raw fruiting body material. The extract ratio is a concentration signal — without it, there is no way to assess whether a milligram figure represents whole mushroom powder or a meaningful extract.
Lion’s Mane Mushroom (Hericium erinaceus) — 300mg Per Serving
Lion’s Mane is the most studied functional mushroom in the cognitive support category and the headline ingredient in the Gusupy formula. Research has focused on two groups of bioactive compounds: hericenones (found in the fruiting body) and erinacines (found primarily in the mycelium). Both have been studied for their potential relationship with nerve growth factor (NGF) synthesis pathways — a protein involved in the maintenance and differentiation of neurons.
Several small human clinical trials, primarily from Japan, have examined Lion’s Mane in the context of cognitive performance and mood outcomes in older adult populations. Results are preliminary, sample sizes are small, and the research field is still developing. None of this research was conducted on the Gusupy finished product.
At 300mg with a 10:1 extract ratio, the Gusupy Lion’s Mane serving is within the range used in available supplement research.
Reishi Mushroom (Ganoderma lucidum)
Reishi has one of the longest histories of use in traditional East Asian wellness practices and one of the most extensive research bodies of any functional mushroom. Its primary bioactives are triterpenes (ganoderic acids) and beta-glucan polysaccharides. Research has examined Reishi primarily in the context of immune system modulation, adaptogenic stress response, and sleep quality markers. It is typically the “calming” or immune-associated anchor in multi-mushroom blends.
Cordyceps Mushroom
Cordyceps — typically Cordyceps militaris in supplement form — is studied primarily in the context of cellular energy metabolism. The key bioactive compound is cordycepin (3′-deoxyadenosine), a nucleoside analog investigated for its relationship with ATP production pathways at the cellular level. Athletic performance and endurance is an active area of Cordyceps research, though human study results are mixed and most trials are small. It is the energy-associated component in most multi-mushroom formulas.
Chaga Mushroom (Inonotus obliquus)
Chaga grows parasitically on birch trees and has an unusually high antioxidant profile shaped significantly by its host. It concentrates betulinic acid derivatives from birch bark alongside melanin compounds and triterpenes. Research has examined Chaga primarily in the context of oxidative stress markers and immune function. Its ORAC antioxidant score is among the highest measured in naturally occurring substances.
Interaction note: Chaga has shown anticoagulant properties in research contexts. Individuals taking blood thinners should consult a healthcare professional before using any supplement containing Chaga. See the functional mushroom gummies safety guide for a full interaction overview.
Turkey Tail Mushroom (Trametes versicolor)
Turkey Tail is one of the most clinically researched functional mushrooms. It contains two characterized polysaccharide compounds: Polysaccharide-K (PSK / Krestin) and Polysaccharide-Peptide (PSP). PSK has been studied in clinical oncology settings in Japan as an adjunctive compound — important context, though this research applies to isolated clinical-grade PSK, not dietary supplement products. Turkey Tail also contains prebiotic fiber studied in the context of gut microbiome diversity.
Maitake Mushroom (Grifola frondosa)
Maitake contains a distinctive beta-glucan structure called D-fraction, which has been studied in the context of immune modulation and blood glucose regulation. Maitake is also a culinary mushroom with a broad nutritional profile, and its inclusion in multi-mushroom formulas serves both functional and nutritional dimensions.
Shiitake Mushroom (Lentinus edodes)
Shiitake is one of the most consumed edible mushrooms globally. Its functional supplement profile is anchored by eritadenine — a compound studied in the context of cholesterol metabolism — and lentinan, a beta-glucan explored in immune research. Vitamin D content is notable in sun-dried Shiitake preparations.
White Button Mushroom (Agaricus bisporus)
White Button is the world’s most commercially cultivated mushroom. In supplement contexts, it is studied for its selenium content, the antioxidant amino acid ergothioneine, and conjugated linoleic acid (CLA). Preliminary lab research has also examined its potential relationship with aromatase enzyme activity, though this research is early-stage.
Black Fungus Mushroom (Auricularia auricula-judae)
Also called Wood Ear mushroom, Black Fungus is widely used in East Asian cuisine. Its supplement profile includes a distinctive polysaccharide content, water-soluble fiber, and iron and potassium levels above most other edible mushrooms. Research has examined its relationship with blood viscosity markers and immune function.
Royal Sun Mushroom (Agaricus subrufescens / blazei)
Royal Sun has a strong research base particularly in Japan and Brazil, where it is cultivated and studied in the context of immune function and metabolic markers. Its primary bioactives are beta-1,3-D-glucan and beta-1,6-D-glucan structures — among the most characterized structural polysaccharides in functional mushroom immunology research.
Needle Mushroom / Enoki (Flammulina velutipes)
Enoki is a familiar culinary mushroom with a functional profile built around its ergothioneine content and polysaccharide structures including flammulin. Some research has examined its prebiotic characteristics. It is a lower-profile ingredient in multi-mushroom blends relative to Lion’s Mane or Turkey Tail, but contributes to the overall beta-glucan and antioxidant amino acid profile of the blend.
Oyster Mushroom (Pleurotus ostreatus)
Oyster mushrooms are a nutritionally dense culinary species with a functional supplement profile that includes naturally occurring lovastatin — a compound that shares structural similarities with pharmaceutical statin drugs. This is relevant context for anyone taking cholesterol-lowering medications. Research has also examined Oyster mushrooms for their beta-glucan content, ergothioneine, and broad amino acid profile.
Interaction note: Individuals taking statin medications should consult a healthcare professional before using supplements containing Oyster mushroom. See the functional mushroom gummies safety guide for details.
The Case for a 12-Mushroom Blend
Multi-mushroom formulas like the Gusupy blend exist because different species contribute meaningfully different bioactive compound profiles. A 12-species formula provides a broader range of beta-glucan structures, triterpenes, ergothioneine, and specialty compounds than any single-species product. The tradeoff is per-species dose concentration — a single-species Lion’s Mane product can deliver 500–1,500mg+ per serving, while a multi-mushroom blend distributes serving weight across all ingredients.
Whether breadth or depth serves a particular buyer better depends on their primary reason for supplementing. For more on how to make that decision, see the best mushroom gummies 2026 comparison and the guide to what to look for when switching to mushroom gummies.
View the Gusupy Formula
View the current Gusupy Super Mushroom Gummies listing on Amazon for current pricing and availability.
All ingredient-level research cited above is based on studies of individual mushroom species or isolated compounds and does not constitute claims about the Gusupy finished dietary supplement product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use.
Disclosure: Top Shelf Mushrooms may earn an affiliate commission on qualifying purchases. Editorial content is not influenced by affiliate relationships.
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